Sentence examples for binding potential of the from inspiring English sources

The docking studies also confirmed the binding potential of the compounds at the ICL active site.

If two compartments are present for [N-methyl-11C]mirtazapine in the cerebellum, then methods E and F may underestimate the binding potential of the radioligand [16].

Substitution of electronegative sulfonyl group at R3 position enhanced the binding potential of the molecule by interacting with Ser353 (Figs. 5, 6).

A partial loss of the functional bisphosphonate moiety due to stabilizing the 177Lu III) complex might reduce the binding potential of the bisphosphonate group to the bone and thus reduces the affinity of the [177Lu]NO2APBP compound to the target tissue in contrast to the 68Ga III) complex.

Flow cytometry of the IL13QD and exosomes from the culture media and cerebrospinal fluid (CSF) of patients with glioma tumors indicated a distinctly populated complex pattern different from that of non-targeted quantum dots and bovine serum albumin (BSA) conjugated quantum dots confirming specific binding potential of the IL13QD to the tumor associated exosomes.

We investigated the phospholipid binding potential of the PDCD10 recombinant proteins using Membrane Lipid Array and PIP-Arrays (Echelon, USA).

For most of the genes we call indirect targets, however, failure to detect binding cannot be attributed to low ChIP sensitivity because the predicted binding potential of these genes is no higher than that of average gene in the genome.

The two-tissue compartment model provided a direct estimate of the binding potentials of [N-methyl-11C]mirtazapine in brain regions, while binding potentials of the single-tissue compartment model and the graphical plasma input model were estimated indirectly from ratios of distribution volumes in brain regions.

The use of both positive controls (such as diethylstilbestrol and ethinyl estradiol) and a negative control (such as testosterone) would provide validation of the analysis and allow for the quantification and comparison of the two test substances in relation to the binding potentials of the controls.

The heparin-binding potential of the fourth LRR domain is therefore likely to vary among Slit homologues, which might be important for modulating the functional properties of different Slits.

This disrupts the binding potential of canadine with the G-quadruplex thereby exhibiting no biological activity in the TT cells.