Sentence examples for binding potential of a from inspiring English sources

We use this approach to identify miRNA binding potential of a set of approved drugs, suggesting a probable novel mechanism of off-target activity of these drugs.

Grooves or scratches that are in the order of bacterial size increase the contact area and hence the binding potential, whereas grooves that are much larger-wider than the bacterial size approach the binding potential of a flat surface.

Alternatively, we can also quantify the binding potential of a TF to all genes, resulting in a continuous representation of TF-gene regulatory relationships [ 31- 33].

The binding potential of a target transcription factor, therefore, can be partially learned from the co-binding proteins and features that jointly participate in a regulatory module within the cell.

But the BASE method does not use a determined target gene set, instead, it utilizes the binding affinity profile that reflects the binding potential of a TF to genes.

To estimate the binding potential of [11C]CB184, a reference tissue model may be useful for quantification of TSPO.

In addition, the binding potential of [F]MPPF, a 5-HT1A receptor ligand, could not be correlated to 5-HT synthesis rates as measured with [C]AMT in the raphe nuclei [ 93].

Serine 307/312/314: Three serine residues (S307/312/314) in the PEST domain of THOC5 have been shown to be directly phosphorylated by Ataxia-telangiectasia-mutated (ATM) kinase [ 15] followed by loss of the RNA binding potential of THOC5 [ 10], suggesting a novel connection between DNA damage and RNA export machinery.

The predicted binding energy reflects the binding potential of the miRNA to the target site: a lower binding energy indicates a higher binding potential.

The binding potential of (R -[11C]verapamil was assessed using a pR -[11C]verapamiled constrained twastissue plassessedusingmpartment model and used as outcome measure.

The uptake of radiolabelled D2R antagonist [I]IBZM [ 14] reflects the proportion of D2Rs not occupied by endogenous dopamine, and is therefore an indirect measure of endogenous dopaminergic tone, i.e. higher levels of endogenous dopamine are associated with a lower binding potential of [I]IBZM, according to the competition model [ 25].