Sentence examples for binding potential in the from inspiring English sources

Finally, with regard to binding potential in the brain, we assumed that equilibrium or near-equilibrium binding conditions existed in the brain at the time of peak brain uptake.

We obtained arterial blood samples for kinetic data analysis and found that the compound had a differential distribution in brain regions, with the highest binding potentials in the frontal and temporal cortices, intermediate binding potential in the thalamus, and low binding potentials in the striatum, hypothalamus, and brainstem.

Several factors may have contributed to these results: (1) efflux transporters at the blood brain barrier, (2) low receptor density in humans, (3) lower in vivo binding affinity compared to that measured in vitro, (4) low delivery of the radioligand to brain, and (5) low binding potential in the brain.

After Internet gaming task, C-NMSP binding potential in the striatum was significantly lower in IGD subjects compared with controls, indicating reduced level of dopamine D2 receptor).

As shown in Figure 1c, 57 miRNAs were predicted to have binding potential in the 3′ UTR region of hTERT mRNA (details shown in Supplementary Table 3).

A recent study reported a 26% lower serotonin transporter binding potential in the amygdalae of depressed medication-free patients with bipolar disorder [ 10].

The Areas under the curves of the effects on monoamine concentrations and the binding potentials in the PET-imaging study were compared two-by-two using Mann Whitney U tests.

That assumption may be incorrect for [N-methyl-11C]mirtazapine because multiple components may have been identified by methods A and B (see Figure 3), making method F less appropriate than method E for estimating regional binding potentials in the living human brain.

Bipolar patients had slightly higher binding potentials in the midbrain than the healthy controls, while patients with major depression had slightly lower binding potentials than the healthy controls.

There were no significant differences in binding potentials in the midbrain compared to the mood-disorder patients and the healthy controls.

We have fitted the properties of such intermetallic alloys and compounds utilizing a semi-empirical tight-binding potential in the second moment approximation.