Sentence examples for binding potency in the from inspiring English sources

We observed stronger binding potency in the bioactivated dust samples compared with the raw dust extracts.

The compounds androstenone and galaxolide exhibit strong antagonistic AR binding potency in the AR-CALUX®, having equivalent factor (EF) values of 7.7 and 0.39, respectively.

Based on their REP values and concentrations, these two compounds could explain less than 1%% of the observed TTR-binding potency in the unfractionated extract.

Two compounds could be confirmed to contribute to the detected TTR-binding potency in the sediment sample, i.e., triclosan and nonylphenol technical mixture.

Each RP and NP fraction was tested for its TTR-binding potency in the RLBA, described in detail elsewhere [ 4, 12].

None of the C2-symmetric dimers demonstrated increased potency, however dimer 5j, derived from 4-phenethylamine, was found to have increased binding potency in vitro relative to the parent monomer.

However, the cellular activity of these compounds is rather low in potency relative to the extraordinary subnanomolar binding potency in homogeneous assays in vitro.

Wang, L. et al. Accurate and reliable prediction of relative ligand binding potency in prospective drug discovery by way of a modern free-energy calculation protocol and force field.

Compounds that met acceptable ADME criteria, selectivity, human plasma protein binding, potency shift in the presence of α-glycoprotein were evaluated in rat and dog pharmacokinetics.

19 The increase in binding potency of the phenylpropyl group can also been seen in the increase in potency when added to the clomipramine (E) or chlorpromazine (H) scaffolds.

This effect clearly explains the hyperbolic LE trend not as the real increase in binding potency but by the availability of ligands for the ligand-receptor complexes.