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The binding points within the resin rich regions were found to be the damage initiation sites in all weave types under all loading conditions, which were confirmed with both visual observation and digital image correlation strain maps.
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Besides the use of native and engineered endolysins for controlling bacterial contamination at different points within the food production chain, this also includes the application of high-affinity endolysin-derived cell wall binding domains for rapid detection of pathogenic bacteria.
Lines connect points within the same habitat.
The DNA sequence associated with each of the peaks is a 250 bp fragment that is centered on the highest point peak within the TAF7L binding region as defined by Grizzly Peak.
G-protein binding occurs within the leftmost cytoplasmic loop.
These results also point out sequence-dependent variations in cation binding within the major groove of A-form RNA helices.
While all three point mutations within the ubiquitin binding domain abrogated NEMO's interaction with ubiquitinated RIP1 to a similar degree, there appears to be some small differences in their ability to block cell death.
Following this strategy and guided by our cocrystal structures of STING substituents with DMXAA, we identified two point substitutions within the ligand binding pocket: S162A (reported previously; Gao et al., 2013b) and Q266I, each of which strongly promotes DMXAA recognition.
However, our photo-induced cross-linking experiment pointed to the MTA family proteins rather than CHD3/CHD4 as the direct H3 tail peptide-binding proteins within the NURD complex.
30 A number of distinct alterations have been identified including point mutations within the nucleotide-binding loop in exon 18, small deletions in exon 19 or insertions in exon 20, as well as point mutations in the activation loop in exon 21.
Point mutations within the PML RARalpha ligand-binding domain (LBD) have been found and account for ∼40% of ATRA-resistant APL (Gallagher et al, 2012).
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