Sentence examples for binding pockets for specific from inspiring English sources

Humanized hapten-binding IgGs were designed with an accessible cysteine close to their binding pockets, for specific covalent payload attachment.

Integrins are composed of two non covalently associated subunits (α and β) that form a binding pocket for specific sequences or domains in extracellular matrix (ECM) molecules; the most well known is the tripeptide RGD (argenin-glycin-aspartic acid) domain found in fibronectin and laminin ECM molecules.

In this case, four thymine methyl groups form a hydrophobic binding pocket for a specific valine contact [ 97].

Using high resolution NMR, we solved the structure (Protein Data Bank ID: 2I7U) of a prototypical dimeric four-α-helix bundle, (Aα2-L1M/L38M 2, with designed specific binding pockets for volatile anesthetics.

The dataset was used to develop virtual binding pockets for accommodating HLA-II specific sHLA-II specific

The binding pockets for HT ligand binding are indicated by orange arrows.

Drug target structures are preferably molecules that contain binding pockets for known low molecular-weight compounds.

We found that the brightest readouts are attained when a specific binding pocket for the fluorophore is present on the analyte.

Since the opposite ends of α5, the β-strands and loops participate in forming the binding pocket for GDP, these conformational changes subsequently initiate specific structural modifications in the GDP binding pocket (reviewed in [16]).

A 10 Å sphere around the centre of the binding pocket was defined as binding pocket for the docking runs.

Also, a clear definition of the binding pocket for KZ7088 has been presented.