Sentence examples for binding pocket which recognizes from inspiring English sources

The second β strand, second α helix and a GLGF loop of the PDZ domains collectively form the binding pocket, which recognizes the hydrophobic C-terminal peptide of a target protein [ 9, 10].

The kinase domain has a broad substrate binding pocket, which preferentially recognizes double-stranded substrates with recessed 5′ termini.

One approach is to identify molecules that occupy the pterin binding pocket which is distinct from the pABA binding pocket that binds sulfonamides.

FhGAPDH lacks a binding pocket which has been exploited in the design of novel antitrypanosomal compounds.

Majority of small molecule kinase inhibitors reversibly occupy the ATP binding pocket, which means that they are ATP-competitive inhibitors.

In comparison with the S5 S1 pockets, the prime-side binding pockets, which interact with the P′ residues downstream of the cleavage junction, are less well defined.

iDTP predicted that the CoA binding site on hPPARγ-LBD is the receptor's ligand-binding pocket, which also binds rosiglitazone and CD5477.

Such conformational changes facilitate the formation of an ephrin-binding pocket which accommodates a phenylalanine residue, Phe120ephrinB2.

Additionally, the SRL is proposed to host several cation-binding pockets, which could facilitate platinum coordination.

The anchor residues for HLA-A2 fit into narrow and specific-binding pockets, which allow almost only P2 Met and Leu for pocket B and Pc Val and Leu for pocket F (Guo et al., 1993).

A similar binding pocket is seen in the PARP1 mononuclear treble clef (PDB identifier 4AV1_A), which recognizes and binds dsDNA [ 54] (Additional file 6: Figure S5).