Sentence examples for binding pocket was also from inspiring English sources
In addition, H334 residue that is structurally nearby the binding pocket was also examined.
In the case of KSHV protease, however, the substrate binding pocket was also occluded by a loop (residues 17 21, Figure 18).
Three of the remaining residues of the H2O2 binding pocket are also conserved in rPsaDyP, whereby in the DyP-type peroxidases from P. sapidus and P. ostreatus leucine is exchanged for valine (rPsaDyPV363).
Biophysical and genetic studies to identify the binding pocket are also carried out.
The S3 binding pocket is also well-defined, whereas the S4 pocket is very large and can tolerate a range of capping groups that are likely to contribute to potency by picking up further hydrophobic interactions.
The structure of aSelBL can be superposed on that of the EF-Tu-Cys-tRNACys ternary complex [ 26], showing that the aminoacyl binding pocket is also structurally well conserved.
In addition to I572 and V576, numerous other surface-exposed amino acids of the acceptor peptide binding pocket are also hydrophobic in PglB C.lari : I317, M318, Y433, V438, Y466, Y468 and V575 [ 11].
The limited space of the alternative binding pocket is also the reason why models of anti-Prelog complexes were only obtained for substrates with methyl groups (1, 21, 22), but not for those with more bulky, substituted alkyl side chains such as 28, 29, or 43.
A close observation of displacements and conformational changes in the residues lining drug-binding pocket was also carried out.
The projection of some of the highly conserved domains that form the ligand-binding pocket suggests that the core structure of the ligand-binding pocket is also likely to be conserved across these FBG domains (Fig. 3).
