Sentence examples for binding pocket that was from inspiring English sources
HSP70 has a binding pocket that was first demonstrated for the ER HSP70 homolog BiP [ 70] and later for bacterial HSP70 [ 71].
Here, we report the development of a versatile alternative FRET sensor containing a de novo Cys2His2 binding pocket that was created on the surface of the donor and acceptor fluorescent domains.
A binding pocket that is likely to bind a ligand will have an Sscore greater than 0.8 and a Dscore greater than 0.83 [44] 44].
Consequently, they form a characteristic "glove" shape, encompassing a hydrophobic binding pocket that is able to bind specific small organic molecules [4].
One obvious common feature of these two groups of GT41 proteins is that both bind sugars donors that are activated by UDP, requiring a binding pocket that is formed by the C-terminal half of the GT-B domain (Fig. 1A) [18], [18].
The relatively smaller OPR3 residues allow formation of a wider substrate binding pocket that is less enantio-restrictive.
The structure of NPC1L1 NTD), while sharing the same overall topology as NPC1 NTD), reveals a cholesterol binding pocket that is closed from solvent, suggesting a gating mechanism that relies on the movement of multiple elements around the cholesterol entrance.
This is a size of binding pocket that is within reach of what are commonly considered drug-like molecules (Lipinski, 2004).
Likewise, the selective conservation of glycines in the glycine rich loop of EPKs appears to confer flexibility in the ATP binding pocket that is absent in ELKs.
The authors proposed a molecular model explaining the interaction with key amino acids of the putative binding pocket that were identified in functional studies.
