Sentence examples for binding pocket of one from inspiring English sources
Additionally, a molecular docking of the most active compounds of each series into the ligand binding pocket of one subunit of human 11β-HSD1 was performed.
The causative mutation was identified in the guanosine triphosphate (GTP) binding pocket of one of the α-tubulin gene (tuba1a).
The nature of the ASCE folds places the ATP-binding pocket of one subunit close to γ-phosphate sensor elements in an adjacent subunit, thereby providing the opportunity for coordinated catalysis and ATP hydrolysis.
A ligand-binding pocket on one face of the sheet is particularly common in other β-sandwich domains, especially those involved in carbohydrate binding - e.g. the CMB4 of xylanases and the DOMON domain.
The structure shows that the solo ASRAH domain from Thermotoga exists as a tetramer with each unit containing a deep cleft that could potentially form a binding-pocket on one face of the sheet.
A conserved YXXXY motif in the heme binding pocket of these NEAT domains, where one tyrosine binds the iron and the other tyrosine is involved in hydrogen-bonding to the axial tyrosine, appears to be key for heme binding, as other NEAT domains lacking this motif do not bind heme.
A comparison of the colchicine binding pocket of bovine and the putative one of Leishmania, showing the peptide backbone as a ribbon diagram where colchicine (CN2) is visible, revealed structural differences related to secondary structure elements of the β-tubulin protein.
One of the most studied macromolecular systems has been the engineered binding pocket of T4 lysozyme.
It is clear that one of the phenol-hydroxyl groups of BPA is indispensable for the interaction with a binding pocket of ERR-γ.
The binding pocket of this compound comprises of HIS44, TYR68, LEU46, GLY61, TYR36, LEU62 and LEU59.
