Sentence examples for binding pocket is the from inspiring English sources

The retinal binding pocket is the most conserved common element of the structure.

The shifted orientation of c52 within the binding pocket is the consequence of an enlarged substituent on the phenyl group of this compound.

In a AAA+ ATPase, the nucleotide binding pocket is the most sequence-conserved region, defined by the essential Walker A and B motifs.

Four analogs with a substitution at one site inside the binding pocket were the first to be tried, but no significant enhancement in affinity was found.

The eight to ten amino acid residues forming the adenylation domain binding pocket are the main determinants of substrate specificity [ 7, 61, 62].

Underscoring the similarities between these binding pockets is the common presence of negatively charged invariant residues (Ling et al. 2008; Shumilin et al. 2012).

One common property of the NADH binding pockets is the presence of an aspartate or a glutamate that is able to interact with two hydroxyl groups of the adenine ribose moiety (Carugo and Argos 1997).

The principle site, the ATP-binding pocket, is the target of many physiological regulators and also most experimental or therapeutic inhibitors, which typically block it in a competitive or allosteric fashion.

Our data suggested that the newly identified substrate-binding pocket is the actual site for catalysis, and PPO activation could be achieved without withdrawing the conserved phenylalanine residue that was previously deemed as the substrate 'placeholder'placeholder

Alternatively stated, the binding pocket is accessible to the octyl chain only in the nonconducting state of the channel.

As an additional case where the binding pocket is narrow and the ligand is small, searching with the structure of an AChE-bound thiocholine query structure was performed.