Your English writing platform
Discover LudwigExact(1)
Experiments to determine if UBIAD1 will accept oligoprenyl diphosphates as a substrate or ligand may be informative, but the 3D protein model clearly shows an optimal binding pocket for this type of compound (Figure 6B and 6C).
Similar(59)
However, the binding pocket for the incoming nucleotide does not have this flexibility, so that insertion of 8-oxodGTP opposite cytosine is strongly discouraged.
This suggests that the binding pocket for the C-2 alkyl substituent in Ch-MAL is designed to bind small alkyl chains and excludes large groups.
The increased mobility near N99C and at the myristate pocket upon ligand binding may seem surprising because Val104 in this loop helps to form the binding pocket for the adenine ring of ATP.
The fact that TaOMT2 catalyzes the methylation of three different substrates: tricetin, selgin and tricin (Fig. 1) raised the question as to whether this enzyme protein possesses one substrate binding pocket for the three substrates, or three different sites.
All residues forming the walls of the binding pocket for the Phe substrate in 1AMU_A as well as residues that bind the adenosine monophosphate AMP moiety were identified.
Finally, we hypothesize that residues L59 and A184 also help define the size of the binding pocket for the glycoside R group.
Molecular docking simulations were carried out and these studies suggested a different binding orientation inside the CDK2 binding pocket for these analogues compared to flavopiridol.
The overall P450 folding conformations are well conserved, and the open access binding pocket for the large macrolide oligomycin C was observed above the distal side of heme.
A prominent feature of cyclin K is an additional helix (H4a) in the first cyclin box that obstructs the binding pocket for the cell-cycle inhibitor p27Kip1.
We found that the brightest readouts are attained when a specific binding pocket for the fluorophore is present on the analyte.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com