Sentence examples for binding pocket for an from inspiring English sources
The structures reveal a 20-strand beta sheet that forms a binding pocket for an extended polyproline motif.
For example, a typical binding pocket for an α-helix is formed by a few adjacent subpockets that collectively form an elongated crevice that can accommodate side chains projecting out from one side of the α-helix.
Also, in contrast to replicative DNA polymerases, binary structures of Dpo4 show that the terminal base pair of the DNA substrate occupies the binding pocket for an incoming nucleotide, implying that the DNA must translocate by 1 bp relative to Dpo4 to allow for dNTP binding.
In this case, four thymine methyl groups form a hydrophobic binding pocket for a specific valine contact [ 97].
In contrast, mSAA3 is α-helical and oligomerizes to form a hollow, largely non-polar interior that could serve as a binding pocket for a non-polar small molecule.
The inferred germline antibody already harbors potential binding pockets for a glycan and a short protein segment.
The predicted conformations were located at the binding pockets for a template chain of RNA and a nucleotide triphosphate.
The latter is known from the cytoplasmic poly(A -binding protein A -bindingons as a binding proteinfor peptides contanding a PAM2 motifunctionsnterasting motif 2; albindingand Lengauer, 2004; Kozlov et al., 2004; Jinek et al., 2010; Xie et al., 2014).
This indicates that DCoA binding facilitates ATP binding by inducing conformational changes in the enzyme and preparing the ATP-binding pocket for a snug fit.
Similarly to Bet v 1-like superfamily members, this protein contains a binding pocket for steroid ligands formed by a long α-helix and an anti-parallel β-sheet.
Inspection of the molecular model of trypsin with Z-Gly-O3G revealed that there is space in the binding pocket for the introduction of a small substituent, such as a methylene (O3G=) or two fluorides (O3GF2), which are weak and strong inductively electron-withdrawing groups, respectively.
