Sentence examples for binding permits from inspiring English sources

Ligand binding permits autophosphorylation of the activation-loop tyrosines.

This binding permits matching of the polymerization with the unwinding rate on the leading DNA strand of the replication fork during normal replication (Lou et al. 2008).

Analyses of the plasminogen-binding protein population by both affinity chromatography and ligand binding permitted the identification of several surface proteins that serve as plasminogen receptors in C. neoformans.

Imperfect (i.e. non-consensus) EREs have been demonstrated to have function when optimally positioned with regards to target TSSs, wherein they can provide sufficient affinity for ERα binding, permit important DNA bending, and favor specific patterns of coregulator recruitment to the target gene promoter [67] [69].

Mutations in the AR can increase its affinity for ligand binding, permitting activation by non-androgenic hormones or even antagonists (Nelson et al, 2003; Debes and Tindall, 2004).

Rather than activation being dependent upon a stoichiometrically equal ratio of CAR to antigen, it seems more likely that the various signalling chains involved upon CAR binding permit one antigen to mediate a network of interchain phosphorylation events.

Rather than dissociating kinesin-1 from mitochondria, Ca(2+ -binding permits Miro to interact directly with the motor domain of kinesin-1, preventing motor/microtubule interactions.

This similarity in binding surfaces permits the pathogenic protein to compete with a host target protein.

Radioligand binding also permits a characterization of receptor subtypes with different affinities and provides an estimate of their relative proportions, especially in the study of central nervous system receptors, where the effects of neurotransmitters are complex, and isolated tissue preparations are unfeasible (Tallarida et al. 1988).

A specific cis-acting element of gene enhancer in CYP3A4 has also identified which confers HNF4α binding and permits PXR- and CAR-mediated gene activation [ 22].

In both cases the loss of a KR short-range repressor binding site permits the enhancer to respond to an input signal from an activator in ectopic embryonic segments (Ho et al. 2009; Shimell et al. 1994).