Sentence examples for binding permit from inspiring English sources

Imperfect (i.e. non-consensus) EREs have been demonstrated to have function when optimally positioned with regards to target TSSs, wherein they can provide sufficient affinity for ERα binding, permit important DNA bending, and favor specific patterns of coregulator recruitment to the target gene promoter [67] [69].

Rather than activation being dependent upon a stoichiometrically equal ratio of CAR to antigen, it seems more likely that the various signalling chains involved upon CAR binding permit one antigen to mediate a network of interchain phosphorylation events.

Ligand binding permits autophosphorylation of the activation-loop tyrosines.

Analyses of the plasminogen-binding protein population by both affinity chromatography and ligand binding permitted the identification of several surface proteins that serve as plasminogen receptors in C. neoformans.

Mutations in the AR can increase its affinity for ligand binding, permitting activation by non-androgenic hormones or even antagonists (Nelson et al, 2003; Debes and Tindall, 2004).

This binding permits matching of the polymerization with the unwinding rate on the leading DNA strand of the replication fork during normal replication (Lou et al. 2008).

Rather than dissociating kinesin-1 from mitochondria, Ca(2+ -binding permits Miro to interact directly with the motor domain of kinesin-1, preventing motor/microtubule interactions.

Bayle, J. H. et al. Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity.

However, these TRF2 PTMs likely disrupt TRF2 dimerization, which may abrogate Myb domain binding but permit basic domain binding.

Polymers with innate binding sites permit the hydrogen-bonding/van der Waals' interactions with APIs, thus leading to drug stability in the matrix system [ 45].

Clearly the dose of SR4554 needs to be enough to ensure penetration into tumour to allow sufficient intracellular bioreduction and binding to permit F quantitation by MRS (Brown and Workman, 1980; Workman and Brown, 1981; Aboagye et al, 1996).