Sentence examples for binding peaks that do from inspiring English sources

Remarkably, CP190 binding peaks that do not contain SU HW) binding (defined as CP190 peaks with an average log2 SU HW binding ratio) <1) are depleted from LADs, without any enrichment at +40 kb.

For each cell line, we divided the GABPα ChIP-seq peaks into two groups based on the presence of CREB1 binding: "GABPα +CREB1" (regions bound by both GABPα and CREB1) and "GABPα −CREB1" (GABPα peaks that do not overlap CREB1 binding peaks).

A further possible explanation for H3Y41ph peaks that do not overlap STAT5 binding sites is that H3Y41ph is laid down by at least one other kinase (Dawson et al., 2009; Griffiths et al., 2011), which may function independently of STATs.

The profile of CP190 binding peaks across LAD borders can therefore be subdivided in peaks that co-localize with SU HW) and peaks that do not (Figure 3b, 2nd and 3rd panels).

Peaks that do not correspond to the reported minimal enhancers largely correspond to 1% FDR chIP-chip bound regions (Supporting File S2), suggesting that some of these binding sites occur outside of minimal enhancers.

We examined two sets of peaks from our data: the peaks that overlap between WT and KO (shared peaks), and peaks that do not overlap between WT and KO (unique peaks).

There were also a number of SRF associated peaks that did not overlap with MKL1 and ELK4 binding sites, indicating that there may be other cofactors utilized by SRF.

Moreover, when we combined IRF5- and RelA-binding data with microarray gene expression data at the same time point, we noted that the peaks of the IRF5 RelA cistrome were centered around the TSS of strongly upregulated genes, whereas the RelA peaks that did not overlap with IRF5 displayed more uniform distribution in both upregulated and downregulated genes around the TSS.

To ensure that selected p300 peaks contain histone modification marks under study, distal p300 peaks that did not overlap any histone modification peaks were excluded.

RAD21 binding peaks that were not overlapping with any of the CTCF peaks, were named CTCF independent RAD21 binding sites (CIB).

We removed binding peaks that overlap with high occupancy target (HOT) regions [ 42, 43].