Sentence examples for binding patterns for key from inspiring English sources
Having identified predominantly cell type-specific binding patterns for key regulatory TFs raised the question as to whether TFs are passively recruited to cell type-specific regions of open chromatin with no major regulatory impact, or whether they actively participate in two different transcriptional programmes.
Concerted mathematical and experimental analysis of global binding patterns for 10 key haematopoietic TFs in both cell types suggests that cell type-specific binding is not opportunistic, but instead makes meaningful contributions to cell type-specific transcriptional control.
Analysis of binding within bidirectional promoters revealed interesting binding patterns for CREB.
Fourthly, it fails to define a binding pattern for each identified differential binding site after comparing two samples.
To perform a comparative analysis of genome-wide binding patterns of the key regulators simultaneously expressed in HPC7 and mast cells, we generated ChIP-Seq data for CTCF, E2A, ERG, FLI1, LMO2, MEIS1, PU.1, RUNX1 and SCL in primary mast cells and also CTCF and E2A in HPC7 cells.
Unexpected binding patterns are observed for oligonucleotides.
The carbohydrate-binding properties of each lectin were responsible for the different binding patterns observed.
As shown in Fig. 6b, G2 has a similar binding pattern to G1 except for some key differences.
Our expectation was that changes in SH2 binding patterns could be correlated with biological responses to inhibitors, and that probes for which binding decreased strongly in TKI-inhibited cells were likely to represent key pathways for TKI action.
For the description of the inhibitors we used features based on their 2D structures, preferred binding partners (primary targets) and binding patterns.
