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Furthermore, a molecular docking of the tested compounds was carried out in order to investigate their binding pattern with the prospective target, VEGFR-2 (PDB-code: 4ASD).
Furthermore, a molecular docking of the tested compounds was carried out to investigate their binding pattern with the prospective target, DNA (PDB-code: 152d).
In order to understand the mechanisms for AS directly under RBM10 regulation, we correlated the RBM10 RNA binding pattern with the splicing changes upon RBM10 OE and KD.
We found a distinct binding pattern with the highest peak at the origin of replication and very low SeqA binding in the terminus region of the chromosome (Fig. 7).
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However, different strains show different binding patterns, with the worldwide dominating genogroup II.4 strains expressing the broadest histo-blood group-binding pattern and thought to be able to infect secretor-positive individuals of all ABO blood group types irrespective of Le status [31].
Thus, it was possible to compare the post-mortem THK5117 binding patterns with the ante-mortem patterns for F-FDG in the same subjects.
Furthermore, molecular docking and molecular dynamics simulation studies verified that compound 12c and 12e shared similar binding pattern with gefitinib in the binding pocket of EGFR.
Such an asymmetric binding pattern with incomplete dehydration is different from the observations in the potassium channels where the K+ ions are completely dehydrated and form strong coordination with eight symmetrically positioned carbonyl oxygen atoms of the protein (Zhou et al., 2001).
This revealed a striking, bimodal binding pattern, with dispersed ORC1/CDC6 binding in the interior of chromosomes and denser binding at subtelomeres.
The species-specific binding pattern with human C4BP is consistent with gonococcal resistance to human serum complement.
We then examined the accuracy by correlating those "Only" binding pattern with their associated genes' expression levels.
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