Sentence examples for binding pattern of the from inspiring English sources
Further molecular docking studies were also carried out to investigate binding pattern of the newly synthesized compounds with ERα.
Molecular docking was performed to study the binding pattern of the newly synthesized compounds with VEGFR-2 active site.
Computer-aided drug design (CADD) tools added a benefit to the design and development of new CDK inhibitors by studying the binding pattern of the inhibitors to the ATP binding domain of CDKs.
The binding pattern of the anti-E1 antibody and the fitting of the structure of the dengue virus E glycoprotein into our 3D reconstructions further suggest that the HCV-LP E1 and E2 proteins form a tetramer (or dimer of heterodimers) that corresponds morphologically and functionally to the flavivirus E homodimer.
The dissimilar binding pattern of the nucleobases produces significant differences in the supramolecular architectures of compounds 1 and 2 which are essentially governed by an extensive network of non-covalent interactions such as hydrogen bonded adenine adenine base pairs, hydration of the nucleobases, carboxylato nucleobase associations, and face-to-face π π stacking.
The root mean square deviation range was 0.0154 0.9753, with all values less than 2 Å, indicating that Surflex-Dock was reliable in causing reappearance of the binding pattern of the ligand, and the parameter setting for molecular docking was appropriate.
Evaluation of similar compounds, along with docking, offered information on the binding patterns of the hit compound.
In order to understand the distinguishing binding patterns of the different blockers, we computed the potential of mean force of the drug binding process.
While the overall binding patterns of the two mAbs had many features in common, distinct differences were observed about the phenyl ring and the methylester group of cocaine.
Overall, TEs were bound by a wide-range of CMs associated with both repressive and activatory chromatin (Fig. 2a, c, d and Supplementary Data 3), and these results demonstrate the interconnected binding patterns of the TEs by CMs through chromatin marks.
