Sentence examples for binding pattern and the from inspiring English sources

Compound 33d, which displayed the highest BACE 1 activity (18.33 ± 2.80 μmol/L) among these two series, was chosen to study the protein binding pattern and the result showed that it was in close contact with two essential catalytic aspartates (Asp32 and Asp228) of the BACE 1.

Besides looking for TEs enrichments and transcription factor binding sites (TFBSs) correlations we also sought to understand if the binding pattern (and the preference for specific families of TEs) of ERα varies as a consequence of the kind of experimental activation of ERα.

Three antibodies specific for ω-5 gliadins (all raised against the N-terminal sequence SRLLSPRGKELGC) gave essentially similar binding patterns, and the results obtained with a single polyclonal antibody and fractions from 'Hereward' are shown in Fig.  2B.

Through sophisticated protocols and assays, sequencing is no longer limited to just reading DNA, but has been creatively adapted to measure transcript abundance, protein-DNA binding patterns, and the three-dimensional configuration of DNA or RNA, among others (see [ 4] for a overview of available applications).

Using Pupasview software [ 15], the rs3738414 is supposed to be located on ESE, and the mutation of rs3738414 perhaps changes the protein binding pattern, and further affects the B7-H4 expression.

Molecular dynamics assays were performed in order to verify the binding pattern and influence of the five DHPMs on Eg5 behavior.

All three compounds showed similar binding pattern and interacts on the active site of IL-2 protein at the surface through several active- site amino acid residues (Figure 3). Figure 3 The docked orientations of Compound 1 (Orange), 2 (Green) and 3 (Pink) in the ligand binding site of IL-2.

Interestingly, under non reducing conditions most of the anti-VEEV scFv phage displayed a nearly similar binding pattern and were able to bind either the E1 or E2 glycoprotein and the corresponding heterodimer (figure 5A).

The molecular docking studies were conducted in order to get insight the binding pattern and extent of binding of compounds with the target enzymes.

Our transcriptome-wide analysis of binding pattern and RBM10 splicing profile allows the illustration of the molecular mechanism underlying RBM10 regulated AS.

Molecular docking study validated the binding pattern and extent of binding of compounds 3 and 4 with the target enzymes.