Sentence examples for binding patches from inspiring English sources

Time resolved FRET analysis demonstrated a very efficient energy transfer for the interaction of EuTC with rich citric binding patches.

The presence of two different binding patches on the carbon nanoparticles surface, one citric acid rich and other glutathione rich, involved the appearance of traps (shallow states) responsible of the two different emission bands.

The structure revealed that IL-10Rβ uses a network of tyrosine residues as hydrophobic anchor points to engage IL-10 family cytokines that present complementary hydrophobic binding patches, explaining its role as both a cross-reactive but cytokine-specific receptor.

The revelation and putative functional assignment of two distinct sub-clusters on the surface of the protein models should enable rational site-directed mutagenesis, including homologous reverse-substitution experiments, to map surface binding patches onto these proteins.

Finally, a detailed study of the binding patches between AROS and Sirt-1 has shown that in Sirt-1 there is a conserved pharmacophore pocket composed by basic residues at the top of the cavity, acidic residues at its bottom and hydrophobic residues as edges.

The interface consists of two major binding patches.

In addition, R72, located near the C-terminus, was affected, resulting in an extension of the UIM binding patch.

Reflective of their likely functional role residues, including R334, D382 and E383, around the Mg2+/ATP binding patch are predominantly conserved across these NLRs (Fig. 5).

Thus, we do not favor the hypothesis that it is possible to disrupt recruitment of Rad23 and Dsk2 by mutating a single binding patch on Rpn1.

In fact, the recent structure of Drosophila Robo Ig1 2 in complex with heparin shows that the Robo and Slit D2 heparin-binding sites are in close proximity, resulting in a continuous binding patch (Fukuhara et al, 2008).

Thus, the same binding patch on the PRL-R ECD recognizes two distinct binding interfaces on each of two different hormones, yet each hormone activates a distinct biological outcome.