Sentence examples for binding partners that can from inspiring English sources
BECN1 has a number of binding partners that can positively or negatively regulate the autophagy core complex.
Thus, we identified nuclear FAK binding partners that can interact, directly or indirectly, with five of the six main regulatory elements reported to control transcription of Ccl5 in multiple cell types (Fessele et al., 2002).
One further level of control of ATF4 resides in its interaction with binding partners that can directly inhibit its transcriptional activity, such as CHOP (58), neuronal cell death inducible putative kinase (NIPK) (23) and, as we and others (3) have reported, DISC1.
These co-factors can have other binding partners that are themselves regulated by different signalling pathways.
Our data highlight UL141 as a non-TNF family protein that can interact with the ectodomain of the TRAIL DRs, providing further evidence for TNFR binding partners that extend outside of the canonical family.
There are binding partners that demonstrate preference for each of the known arrestin conformations: free, receptor-bound, and microtubule-bound.
The larger (130 kDa and higher) DISC1 species can be hypothesized to arise through DISC1 forming high binding affinity protein complexes, either as DISC1 oligomers or with protein binding partners, that remain intact under standard experimental conditions.
Likely it requires binding partners that aid in vesicle nucleation, localization, targeting and recycling.
"We would only consider partnering with an experienced partner that can provide good concepts or methods.
In addition to the non-DNA binding ligand-gated co-regulators, nuclear receptor activity can also be influenced by the binding of other DNA binding partner proteins that can interact with the nuclear receptors to form a cis-regulatory module to enhance or repress the transcription of select target genes [ 3].
Importantly, in the absence of PIP there is a marked reduction of integrin-β1 binding to its binding partners ILK1 and ErbB2 that can be reversed by the addition of fibronectin fragments.
