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RhoGTPases bind to and control the activity of mDia proteins, and several other binding partners of the three mDia1 isoformDia2iand mDia3 havemDia3—have been documented.
To identify new CIA proteins we employed systematic protein interaction approaches and discovered the essential proteins Yae1 and Lto1 as binding partners of the CIA targeting complex.
In summary, our studies suggested that the local environment of residues in a protein is a good indicator to recognize specific binding partners of the protein.
Particularly valuable in this regard are affinity chromatography, to define the binding partners of the peptides, and measurements of the actions of peptides upon binary interactions between presynaptic proteins.
The binding partners of the wild type eIF5B and two mutants were identified by label free quantification (LFQ) using the MaxQuant software.
The goal of this study was to examine integrin-extracellular matrix binding partners of the inner wall basement membrane that facilitate attachment.Human outflow tissues and cultured cells were analyzed by immunofluorescence and western blotting, respectively.
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We have now identified the CCM1 gene as KRIT1, a recently discovered binding partner of the Krev-1/rap1a tumor suppressor gene (Sahoo et al., in press).
We have now identified the CCM1 gene as KRIT1, a recently discovered binding partner of the Krev-1/rap1a tumor suppressor gene (Sahoo et al., 1999).
These screens identified PSD-95, a multiple PDZ domain-containing scaffolding protein, as a specific binding partner of the beta(1 AR-CT.
Interestingly, YAP has also been identified as a binding partner of the pro-apoptotic gene p73, suggesting that in certain cellular contexts, YAP may be pro-apoptotic [54, 55].
We have identified Cyclin G as a new binding partner of the ETP Corto in Drosophila melanogaster.
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