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KEAP1 is an adaptor protein that positions its binding partners in close proximity to CULLIN3 ubiquitin ligase for ubiquitination.
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Most proteins bind their binding partners in the native confirmation.
Cotelle, V. et al. 14-3-3s regulate global cleavage of their diverse binding partners in sugar-starved Arabidopsis cells.
These studies reveal mechanisms and antagonistic partners for specific IAPs, and provide a powerful technology for labeling binding partners in transient protein-protein complexes.
The fluorescence arm of the screen, however, would detect binding partners in pools containing pore blockers.
Then, we searched for binding partners in the nucleus, in particular signaling key molecules.
It is shown in Table 3 that 23.6% of the residues in the W-patterns are close to the binding partner in protein-protein complexes within 5Å.
However, Ku70 was not identified as a dysbindin-1 binding partner in our pull-down screening.
A candidate binding partner in the cytoplasm is PFK2/FBPase2 [11,12].
"But there's mutual interest among the partners in closing the plant down.
It is generally accepted that phosphorylation-independent interactions between 14-3-3 14-3-3 14-3-3ng pandners occur itsa manner similar to that of the binding partnerspS-RAF.
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