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Additional binding partners have also been reported within the past year, including NANOG and IDAX (Costa et al., 2013; Ko et al., 2013).
Axon guidance proteins and their relative binding partners have also an emerging role in the pathogenesis of several neurodegenerative and psychiatric diseases such as schizophrenia [46], [47].
Structures of AR domains in complex with their binding partners have also been determined by both NMR (13) and crystallography.
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Interactions between PDZ domains and internal regions of their binding partners have been also reported, though they are less common [ 2, 11, 12].
Exportin-5 also transports other small RNAs and several protein binding partners have been identified including ILF3 (Interleukin enhancer binding factor 3) [ 80], the ILF3-binding protein JAZ [ 81], and the previously mentioned RNA-binding protein Staufen2 [ 74].
Only few MDGA binding partners have been discovered so far.
Similarly, PTB is also known to interact with mRNAs that encode proteins with a diverse range of functions and some of its binding partners have been identified.
In the past 4 decades of desmin research, a growing number of desmin binding partners has been described (see also a previous review on desmin interactions [ 38]).
Recently, several LASP-1-binding partners have been identified.
A number of Ctn2-binding partners have been identified to date which together suggest that it functions primarily through modifying the activities of its binding partners.
To date, however, no binding partner has been reported for TMEFF2.
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