Note that H-NS and any other Hha-binding partner were present in the cells during this experiment and thus the identified targets should be physiologically-relevant.
Furthermore, in a complex biological system in which multiple interacting partners are present, the effect exerted by a ligand also depends on binding selectivity, i.e., the relative binding affinity toward a target when compared to other proteins.
Another typical case is that binding partners are phosphorylated on binding sites and bind other effectors.
The evolution of GKPID's peptide-binding functions could have conferred spindle orientation only if its binding partners were already present.
It is clear that the RNA levels of some binding partners are increased and of some binding partners decreased.
For example, HSP30, encoding a Nha1 binding partner, and ARR3, encoding an Ena2 binding partners are strongly up-regulated.
For women whose partners were present at the birth, a fourth factor was identified 'Partner Involvement'.
The notation of these binding partners is analogous to the notation of species, however, the binding partners do not have to be defined in the section #molecules.
The following description of desmin interactions is confined to binding partners that are present in muscle cells, i.e., IF proteins, IF-associated proteins, sarcomeric proteins, membrane-associated proteins, small heat shock proteins, apoptosis-related proteins, and nucleic acids.
Such slower motions in one binding partner are thought to be necessary for conformational adjustments that better accommodate the binding partner (57).
