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Here we show BUBR1 as a direct binding partner of all B56 family members using yeast two-hybrid screening.
Given that BUBR1 was isolated as a binding partner of all B56 subunits, we wished to determine if the B56 BUBR1 interaction is essential for promoting chromosome congression.
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By tagging every protein with either a fluorescent protein or an affinity tag, they have made it possible to look at the localization, amount, and binding partners of all proteins.
The addition of a lateral binding partner to all, or a subset of subunits along the filament, either through a neighbouring matrix or indeed another filament creates opportunities for complex and emerging properties of the resulting systems.
Although the binding partner of A38 on OPV particles is still unknown, it must be highly conserved and present on all different OPV.
Hara, K. et al. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.
Mass spectrometry and crosslinking studies demonstrate that eIF3d is a direct binding partner of DAP5.
Moreover, RECK is the predominant binding partner of GPR124 in rat brain blood vessels in situ.
Furthermore, β-catenin, a binding partner of ALK in NB cells, can provide significant hindrance to the crizotinib ALK binding, especially when it is highly expressed22.
Also β-catenin, an important binding partner of E-cadherin, was processed.
FN is a binding partner of GAG, collagen I and other components of the ECM and facilitates network formation26,27,28.
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