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To date, however, no binding partner has been reported for TMEFF2.
No binding partner has been identified for LD3.
Despite the requirement of co-receptors for signaling no other binding partner has been uncovered.
All isoforms regulate complement in an equivalent manner, and no binding partner has been shown to modulate C4bp complement regulatory activity.
To date, only one binding partner has been reported for these proteins: SmTAL3 interacts with a dynein light chain and, presumably, other unidentified proteins in a 90 kDa complex [18].
The genome sequence of strain Mic-PCC7806 revealed a gene coding for a lectin (mvn; mic3128), which binds specifically to a sugar moiety present on the surface of Mic-PCC7806 cells, and a binding partner has been identified in the lipoplysaccharide fraction [ 39].
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The interaction of XPA and its binding partners has been extensively studied; however, the structures of the full-length XPA DNA complex remain to be defined.
In the past 4 decades of desmin research, a growing number of desmin binding partners has been described (see also a previous review on desmin interactions [ 38]).
In the yeast protein-interaction network, the observed negative correlation between the connectivity of a protein and the average connectivity of its binding partners has been seen as a possible adaptation which allows the network to be resilient to the propagation of deleterious perturbations [ 14].
Some binding partners have been identified, including Raptor [29], which binds to substrates and presents them to Tor for phosphorylation, and LST8 [31], [31], which stabilizes the TOR complex.
With respect to apoptosis inhibition, at least three binding partners have been identified in the cytoplasm; the apoptosis signaling kinase 1, the thioredoxin-interacting protein and actin, where actin protects Trx-1 from degradation and preserves its anti-apoptotic function [17, 21].
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