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The decreased recruitment of HTRA2 and SMAC to CD40 in TRAF2-deficient B cells may be related to the decreased recruitment of cIAP1, a potential binding partner for both HTRA2 and SMAC [12], [13], [14].
Antibodies against Arnt (HIF-1β), a common binding partner for both HIF-1α and HIF-2α, p300, SRC-1, and SRC-3 efficiently precipitated the 3' enhancer region of the EPO gene in a hypoxia-dependent fashion (Fig. 2A), indicating that each associates with this region in response to hypoxic induction.
Additionally, the kinase Itk is also a binding partner for both SLP-76 [ 12] and TSAd [ 8, 21, 41].
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We propose that the experimental quantification of all major in vivo binding partners for both VEGF and sVEGFR1 from peripheral blood samples to be essential in reconciling the apparent contradiction between predicted and measured VEGF-sVEGFR1 complexed fractions.
Progress on this issue is likely to require identification of further binding partners for both proteins.
Furthermore, yeast two-hybrid cloning identified metastasis-associated GPI-anchored C4.4a protein and extracellular alpha-dystoglycan (DAG-1) as binding partners for both hAG-2 and hAG-3.
Moreover, Smad1/Mad is a direct binding partner for YAP/Yki in both Drosophila and humans [11, 36].
Koutsioumpa M, Poimenidi E, Pantazaka E, Theodoropoulou C, Skoura A, Megalooikonomou V, et al. Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor.
Shi, L., Jian, K., Ko, M. L., Trump, D. & Ko, G. Y. Retinoschisin, a new binding partner for L-type voltage-gated calcium channels in the retina.
HIF-2α is an alternative binding partner for HIF-1β and appears to have overlapping but distinct target genes compared to HIF-1α19.
Immunoglobulin superfamily member 11 (IgSF11), a potential target for cancer immunotherapy, was identified as a new and previously undescribed binding partner for VISTA.
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