Sentence examples for binding partner as an from inspiring English sources

Here we identify TCF-4, a transcriptional regulator and β-catenin binding partner as an indirect target of the VDR pathway.

32 STAT3 has been demonstrated as a binding partner as well as a substrate of SIRT1.

In a recent work [1], we used extensive atomistic molecular dynamics simulations with explicit solvent to study the binding of an SH3 domain with its binding partner as a general example for protein binding mediated by modular protein domains.

A key feature of HSP function is the ability to interact with a broad array of protein binding partners as a means to potentiate downstream response pathways or facilitate protein folding.

These findings highlight the potential of DISC1 protein aggregation and recruitment of binding partners as a biological mechanism in a subset of mental illness cases, and while the current study only analyzed post-mortem brain tissue, it highlights the possibility of DISC1 being a useful biomarker in future for diagnosis, particularly if these results were also noted in more accessible tissues.

Bora was first identified as a binding partner of Aurora A in Drosophila (Hutterer et al. 2006).

In this context it is also worth mentioning the potential role of the BRCA1 binding partner BARD1 as an essential gene for MDA-MB-231 cell growth.

We identified calcium modulating cyclophilin ligand CAMLG/CAML as a binding partner by a yeast two-hybrid screen of a brain library.

We initially identified GbpB as a binding partner of RpkA, an unusual G protein coupled receptor (GPCR) which functions in phagocytosis and antibacterial defense in D. discoideum[ 33].

By screening of a peptide phage display library, we previously identified profilin-1 as a binding partner for a diabetic aorta-specific phage in rats [8].

It is also possible that in many instances MYCN is not binding directly to DNA sequences, but instead is interacting with another DNA binding partner, such as a methyl binding protein.