Sentence examples for binding parameters obtained from from inspiring English sources
Binding parameters obtained from homologous competition experiments are given in Table 2. Cry2A proteins did not compete for binding with 125I-Cry1Ac, confirming the occurrence of different binding sites for Cry1Ac and Cry2A proteins in this insect species, and in agreement with the susceptibility pattern observed in the resistant insects.
To derive the binding parameters, obtained data were analyzed using modified Stern Volmer equation [24 26].
The error bars were estimated by calculating the s.d. of the set of parameters obtained from all fittings at given temperature.
The resulting values of the pseudo dissociation constant κ (for feedback) and κ′ (for L7Ae-ECFP binding to the second reporter mRNA) were quite similar to those of κ obtained from the single feedback configuration (Supplementary Table 1), indicating that parameters obtained from our simpler system are valid and sufficient to predict the function of a more complex system.
Individual parameter estimates or, when no PK information was available (57 patients), typical population parameters obtained from a previously developed PK model were used to describe the concentration time profiles of sunitinib (no data for the equipotent metabolite SU1266 was available) Information on protein binding was also not available.
Silibinin binding parameters were obtained from the literature; clearance parameters were generated by fitting the PBPK model to plasma concentration time data from hepatitis C patients receiving silymarin (Table 3 ).
