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The binding parameters for the reaction were determined using the Stern-Volmer equation.
In spite of the significant reduction in the response coefficients of cytosolic glucose and arabinogalactan versus a number of kinetic and binding parameters for the parameter-perturbed state, the ρ values of these two metabolites are comparable between states.
Group differences in binding parameters for the corresponding radioligand were calculated using PASW Statistics 18 with independent-samples Mann–Whitney U test, and were considered significant at p < 0.05.
It has been shown for example that the membrane permeabilizing activity of Cry1Ac protoxin is significantly higher for the posterior than for the anterior regions of lepidopteran larvae; although no significant difference in the binding parameters for the protoxin were detected [ 71].
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The similarity in binding parameters for these two radioisotopes suggests that radioisotope selection does not affect the delivery of the antibody to target cells.
Extracted binding data for both midazolam and ketoconazole were fit to Eqs. 4 7 utilizing the statistics software R version 2.12 (ref. 30) and the nonlinear least squares function to determine the binding parameters for either an BI or BC model.
Our results are validated by comparison with DFT calculations [29, 69], which allow us to establish unambiguously our choice of the tight-binding parameters for these systems.
We obtained the most effective combination of four binding parameters for extracting miRNA/target-gene pairs based on the EC value.
Importantly, most estimates do not allow discrimination between the ligand binding parameters for monomeric and dimeric forms of ER.
To directly test this hypothesis and to define the nonspecific binding parameters for IHF, we first adapted a nonspecific finite lattice DNA binding model as outlined by Record and co-workers.
The determination of binding parameters for Aβ16 21 fibers is detailed in Table 5 and Figure 5 figure supplements 1 and 3.
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