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The relative binding parameter of sodium to poly(galacturonic acid) as a function of the degree of neutralization in the presence of excess sodium chloride is determined by 23Na n.m.r. and compared with the numerical results from the Poisson-Boltzmann and the Manning condensation theories.
The strength of drug-target interaction was represented by the binding parameter B. Its values were based on binding constants found in the PDSP Ki database [ 25].
Factor analysis was employed as a confirmatory test whether the binding parameter (Yret or DVR) could be reproduced at these 10 imaging time points.
These data support a kinetic proofreading model where the principle binding parameter controlling T cell activation is the TCR off-rate or mean dwell-time.
The problem with this approach is that different analysts can propose and select different models and thus extract different binding parameter estimates from the same data.
To investigate the binding property of Dat for its substrate and cofactor, ITC measurements were used to accurately determine the binding parameter and thermodynamic characterizations of Dat with dopamine and AcCoA respectively.
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Various binding parameters were evaluated.
Some companies have also set up legally binding parameters for relationships in the office.
Fluorescence data were analyzed and kinetic and binding parameters calculated using Prism (Graph Pad Software).
Data were fitted to equation 1 or 2 and binding parameters are shown in Table 1.
To assess KH176(m) binding to Prdx, we investigated the binding parameters and kinetics by Surface Plasmon Resonance.
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