Sentence examples for binding orientations of a from inspiring English sources

The results of this study are discussed with reference to possible binding orientations of a selected C6-substituted chromone in the active site cavities of MAO-A and -B.

Using molecular docking experiments, this study also proposes possible binding orientations of selected caffeine derivatives in the active sites of MAO-A and -B.

The results of this study are discussed with reference to possible binding orientations of selected caffeine analogues within the active site cavities of MAO-A and -B.

It is noted that in a recent study by Srivastava et al. in which photolabeling of the human α4β2 nAChR with azidoepibatidine was combined with docking experiments in a α4β2 homology model, evidence for two distinct binding orientations of epibatine was obtained.

Docking study was performed to study the binding orientations of synthesized hybrids towards RT enzyme.

The StyA protein structure was optimized by restrained molecular dynamics to reproduce specific pre-S binding orientations of styrene.

At this improved resolution, the binding orientations of several TRPV1 modulators such as double-knot toxin and resiniferatoxin were clearly defined.

Molecular docking study revealed the binding orientations of curcumin analogues in the active sites of COX and thereby helps to design novel potent inhibitors.

Molecular docking study revealed the binding orientations of stellatin and its derivatives into the active sites of COX-1 and COX-2 and thereby helps to design the potent inhibitors.

The binding orientations of compound 32 and 46 (Figure 6) revealed that compound 32 maintained its interactions with the active site residues in wild type as well as in mutated protein while compound 46 lost most of its binding interactions in mutated protein as shown in Table 6.

Steric clashes, loss of electrostatic stabilization between an active-site arginine (Arg305) and the phosphonate analog, and a 180° flip of the hexose moiety account for the differences in the binding orientations of the isosteric phosphonate analog and the physiological substrate.