Sentence examples for binding of two cytoplasmic from inspiring English sources

This triggers formation of a complex with a second membrane co-receptor, Lrp5 or Lrp6, phosphorylation of both receptors, and binding of two cytoplasmic proteins, Disheveled and Axin, to the complex.

SERCA proteins are evolutionary well conserved and are composed of three cytoplasmic domains (A, actuator; N, nucleotide binding; P, phosphorylation), ten transmembrane (M1 M10) helices constituting the transmembrane gate and small lumenal loops.

We also performed high salt washes of endosome preparations to exclude binding of OS-9 to the cytoplasmic side of the ER.

Altogether, these data suggest that the aPKC PAR complex interacts with the nephrin podocin complex by direct binding between the PDZ domains of PAR3 and two cytoplasmic regions of nephrin, including the CT11 and ICD-A regions.

Most functional ABC transporters are composed of at least four subunits: two transmembrane (TM) domains where the transport process takes place and two cytoplasmic nucleotide binding domains (NBDs) providing the energy required for active transport.

All ABC transporters share a common basic structure which consists of four domains: two transmembrane domains, typically with six transmembrane spans per domain, and two cytoplasmic nucleotide-binding domains which catalyse nucleotide hydrolysis [ 30].

MRPs 1-9 have two transmembrane domains and two cytoplasmic nucleotide-binding domains [20].

A functional ABC transporter system minimally contains two cytoplasmic nucleotide-binding ATPase domains and two transmembrane channel-forming permease domains.

ADAM10 is locked at junctions through binding of its cytoplasmic C terminus to afadin.

Concurrent studies have led to the conclusion that the PAN RNA contributes to KSHV lytic infection by avid binding of the cytoplasmic poly(A -binding protein (PA -binding is relocalized to the nucleus, thereby allowing synthesis of late viral proteins.

Decreases in nuclear Cdk2 concentrations correlated with increased binding of Cdk2 to cytoplasmic p21 and p27.