Sentence examples for binding of transport from inspiring English sources
In addition, in vitro measurements led to the suggestion that the reversible binding of transport factors causes the FG repeats to collapse and open a path (Lim et al. 2006b, 2007b, 2008).
We conducted a mutation analysis to determine whether a genetic mutation was present in the region of E2F-5 associated with the binding of transport proteins to affect the intracytoplasmic localisation of E2F-5 probservedserved in the breast cancer subtypes.
It is clear from the analyses of the residues of Pgp that were contacted by ligands in these docking experiments that no apparent differences in the location of binding of transport substrates versus Pgp inhibitors or modulators could be detected using these techniques.
Polyspecific binding of transported drugs and Pgp inhibitors occurs in a central cavity formed by two TMDs (transmembrane domains), but the precise locations and nature of these binding sites remain poorly defined [ 5, 6].
The repulsive forces exclude nonspecific molecules but can be nullified by the binding forces of transport factors (Lim et al. 2006b, 2007a, b, 2008; Rout et al. 2000, 2003).
Despite the high density of charge in certain FG domains, if and how charge influences FG-domain self-assembly and selective binding of nuclear transport receptors is largely unexplored.
These interactive partners might affect not only binding of the transport cargo, but also motor activity of dynein.
These results were interpreted as evidence of a substrate-induced fit mechanism for the binding of different transport substrates by Pgp.
By using a combination of biophysical characterization techniques, we quantified the binding of nuclear transport receptors (NTRs) to such FG domain films and analysed how this binding affects the swelling behaviour and mechanical properties of the films.
To activate the action of the transporter, no other energy is needed than that of the chemical binding of the transported molecules.
In both of these systems, it has been concluded that the first phase reflects the binding of the transported molecule to the OM TBDR, and that the second slower phase reflects the binding to a cytoplasmic membrane transporter.
