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In yeast, Pol III transcription of tDNAs requires binding of three multimeric protein complexes – TFIIIC (six polypeptides), TFIIIB (three polypeptides) and Pol III enzyme (seventeen polypeptides).
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The mammalian OXPHOS comprises of five multimeric enzyme complexes (CI V).
Mitochondrial respiratory chain consists of four multimeric protein complexes, Complex I-IV (CI, NADH dehydrogenase; CII, succinate:ubiquinone oxidoreductase; CIII, cytochrome bc1 complex; and CIV, cytochrome c oxidase).
V-ATPase consists of two multimeric subunits; one is hydrophilic V1 subunit consisting of 8 components, and the other is hydrophobic VO subunit consisting of 7 components [22].
The OXPHOS system consists of five multimeric protein complexes (I, II, III, IV, and V).
The mitochondrial electron transport chain is composed of five multimeric complexes [ 19].
In species ϕ6, host infection requires binding of a multimeric P3 complex to type IV pili.
Another explanation can be the relatively low local concentration of the integrins in the target area and hence lack of bivalency binding of a multimeric molecule [10, 30, 31].
The similarity of their expression profiles is suggestive of co-ordinate regulation, which is consistent with the requirement for stoichiometric binding of the multimeric complex.
The relative amounts of the four multimeric cpDNA forms were estimated to be about 1, 1/2, 1/4, and 1/8 based on molecular hybridization analysis.
First, we used a cell culture assay, in which Gli protein regulates the expression of a reporter regulated by eight multimeric Gli binding sites [17].
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