Sentence examples for binding of this sequence from inspiring English sources

This was confirmed by our findings that, in ChIP assays, in addition to binding to Rad21, this ERE-associated sequence at 21q22.3 could bind to ERα and that the variant allele of rs2839494 inhibited the binding of this sequence to ERα.

It is possible that rs2839494 affected the binding of this sequence to ERα.

Our reporter gene assay and ChIP results show that the ERE-associated sequence at 21q22.3 has regulatory activity and that rs2839494 and rs1078272 in this region are able to affect the binding of this sequence to ERα and Rad21, respectively, resulting in a difference in ERα-activated expression of the reporter gene and suggesting that Rad21 promotes ERα-regulated transcription.

Binding of this sequence to Sp transcription factors has been observed in electrophoretic mobility shift assays and by chromatin immunoprecipitation studies.

Furthermore, these 21q22.3 SNPs (rs2839494 and rs1078272) could affect the binding of this ERE-associated sequence to ERα or Rad21 (an ERα coactivator), respectively, which resulted in a difference in ERα-activated expression of the reporter gene.

The H-region of DmsA and TorA determined binding to either DmsD or TorD; however, how the H-region was defined within that study eludes to the importance of the 38PFSR41 portion of the DmsAL for binding to DmsD, as omission of this sequence did not allow binding to occur.

The HER2 upstream regulatory region contains a conserved Ets-binding site and mutation of this sequence reduces transcription of linked reporter genes in several different mammalian cell lines, including breast tumour cell lines (Scott et al, 1994).

Isothermal titration calorimetry methods show that the binding affinity of this new sequence is slightly tighter than the existing cocaine-binding aptamer.

Moreover, the authors demonstrate that the binding of this transcription factor to sequences within the caspase-8 gene sensitizes cells to TNFα or drug-induced apoptosis [ 46].

An evolutionarily conserved [ 53, 70- 73] AhR repressor (AhRR) specifically blocks AhR-dependent CYP1A1 activity by competing for the AhR binding partner ARNT and by blocking binding of this complex to recognition sequences in target genes [ 53, 70].

Analysis of potential binding sites for mRNA targets of this sequence was ruled out by screening for potential sequences in the human transcriptome: only partially complementary sequences (13 bp at maximum) of unrelated genes were found.