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Further, even though the binding of this phenotype is modest, increased interactions can be seen with IFN-γ-stimulated cells (Fig. 1B and C).
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Types are Process: a generic process which transforms a set of entity pools into another Omitted process: a process which exists but is not shown on the map in detail Uncertain process: a process which may not exist Association: a non-covalent binding of objects Dissociation: a rupture of a non-covalent binding of objects Phenotype: a process which generates phenotypes.
The reversibility of this phenotype is discussed.
We therefore determined cocrystal structures to allow us to understand the molecular basis for EPCR binding and to rationalize how sequence diversity is compatible with the retention of this binding phenotype.
showed that Ca2+ binding activity of CALR is more important for this phenotype than the loss of chaperone function.
Importantly, reintroduction of Rab21 rescued this phenotype.
To assess the potential role of non-var2CSA PfEMP1 variants in PAM pathogenesis, we characterized the binding and antigenic phenotype of BeWo selected parasites.
This band appeared to be specifically sialylated during transition from the high PNA binding, low tumorigenic phenotype of D2.0R cells to the low PNA binding, highly tumorigenic phenotype of cells isolated from tumours resulting from s.c. implantation of D2.0R cells.
Consistent with this phenotype, genome-wide characterization of Dimm binding sites has led to the identification of a number of potential mediators of this process (Hadzic et al. 2015).
While K42A does not interfere with the binding of paromomycin directly [5], the hyperaccurate phenotype of the variant K42A ribosome in part functionally antagonizes aminoglycoside-induced misreading.
Whether this phenotype is a result of its direct interaction with actin in cells, modulation of vinculin-F-actin binding, or other downstream signals, remains to be determined.
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