Sentence examples for binding of this mutant from inspiring English sources

We directly show that lipid binding of this mutant is connected to an open lid conformation demonstrating the impact of the exposed amino acid residues and their participation in binding at the water-lipid interface.

Since the L157A optineurin is still capable of interacting with itself (Fig. 7A), the lack of foci formation in L157A optineurin-GFP-expressing cells, in comparison to the wild type and the E50K counterparts, may be related to the perturbed binding of this mutant to Rab8 (Fig. 7B) and TfR (Fig. 7C) and perhaps other as-yet-unknown leucine zipper-binding protein(s) as well.

This is in agreement with the tight mismatch dNTP binding of this mutant formerly reported (22).

Indeed, the binding of this mutant is reduced compared to WT MutL.

However, by normalizing the binding of this mutant version of Spt16 to Rpb3 binding, it is clear that this minor decrease in Rpb3 binding alone cannot account for the reduced binding of this mutant version of Spt16 across SRG1.

It was reported that the loss of irreversible binding of this mutant is due to a lack of toxin insertion into the membrane [ 28, 61].

As predicted, Tld binding to this mutant form of Sog is weaker as the Collagen IV enhancement is lost.

The R97 mutant displayed even a robust increased inhibitor potency on TLR5 mediated IL-8 production, which may be related to the reduced IRAK-4 binding possibilities of this mutant and therefore potentially increased IRAK-2 binding events.

These new and enhanced interactions between Be and QacR(E58Q) are consistent with the modestly improved binding affinity of this mutant for Be compared to wt QacR (Table 2).

Specific binding of this TetR mutant to the respective mixed tetO-wt/4C5G variants containing one wild type and one double exchange operator half site was only accomplished at a low expression level of TetR variant, while cross-talk with other operator variants were observed at an elevated expression level.

The resistance of ODC_N125K/M140K to rescue by AZI may result from the tighter binding of this double mutant to AZ as compared with ODC_WT.