Sentence examples for binding of this fusion from inspiring English sources

Leukemogenesis induced by AML1-ETO involves binding of this fusion protein with p300/CBP, acetylation of the fusion protein by p300/CBP, and the activation of target genes.

Malignant cell transformation by BRD4-NUT involves binding of this fusion protein with p300/CBP, translocation of this complex to nuclear foci, and stimulation of p300/CBP catalytic activity at these foci.

Binding of this fusion protein was detected by a PE-conjugated anti-human IgG secondary antibody (Sigma Aldrich).

Using this analysis, the binding of the fusion proteins was estimated to be slightly higher, with Kd values from 1.3 9.6 n M. CPG2(Q)3-H6 protein did not compete for [I]VEGF binding in this assay (Table 3).

This result strongly suggests that the binding of the fusion protein to A431 cells is mediated by its specific interaction with EGFR.

Upon binding of the fusion protein to the cell of interest, the diphtheria toxin is internalized which results in protein synthesis inhibition and subsequent cell death.

MLL-Af4 induces a B ALL distinct from MLL-AF9 through differential genomic target binding of the fusion proteins leading to specific gene expression patterns.

The binding of the fusion construct to the angiotensin receptor (AT1) was similar to AngII, and the arterial contraction was 16 ± 1% of the response observed with norepinephrine.

The modified intein contained a Bacillus circulans chitin-binding domain which allowed binding of the fusion protein on a chitin column and could be induced to undergo in vitro peptide bond cleavage which specifically released Cre from the column.

The no-Ter/wild-type Ter signal ratio (−TER/+TER) is 0 for Cy5 and 0.12 for Cy3, consistent with significantly higher binding of the fusion protein to plasmid containing wild-type Ter as compared to plasmid without any Ter.

Previous versions of a negative-dominance system with λ cI repressor fusions utilized two constructs: a λ cI repressor fusion that could homooligomerize and a λ cI repressor fusion with a mutation in the helix-turn-helix DNA binding domain that abolished binding of the fusion to DNA [19].