Sentence examples for binding of these substrates from inspiring English sources

It was hypothesized that any changes in uptake rates of Mitoxantrone are due to competitive binding of these substrates to BCRP.

However, we observed no significant difference in the structural determination of XPA binding to these substrates.

For example, Lp(a) binding to immobilised fibrinogen and fibrin results in the inhibition of plasminogen binding to these substrates [ 24, 25].

These data indicate that numerous mutations distal from the active site contribute to enhanced 'uniform binding' of the substrates, which is the first step in the evolution of novel catalytic activity.

The first step is recognition and binding of the substrates by the recombinase [23].

The results also indicate that binding of these inhibitory substrate analogues to the proximal niche of the Qo domain significantly increases the ΔG‡ for reduction of C1.

These data have shown the great diversity of sizes, shapes, and modes of binding of the substrate binding sites of these mammalian cytochromes P450.

Cells were co-transfected with Skp2-V5 and β-TrCP-V5, with the objective of comparing binding affinities of these substrate receptors to Cul1 upon SAP130 overexpression.

These findings suggest that the binding of the substrate to the catalytic domain is impaired in the absence of PHD1.

It has been shown that binding of one of these substrates (ferredoxin or NADP+) weakens the binding of the other.

When riboswitches were first discovered, two questions immediately arose: how is the metabolite recognized, and how does binding of the substrate trigger genetic regulation?