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Via the binding of the specific DNA sequence, the engineered nucleases can proficiently cleave the targeted genes.
CD138 expression was studied upon equilibrium binding of the specific B-B4 antibody to the human breast cancer MDA-MB-468 cell line.
On the contrary, upon binding of the specific target protein onto the primer through the protein-small molecule interaction, the HCR will be inhibited due to the steric and allosteric effect.
Predicted amino acid sequence homology for the SBDP120 cleavage site, and binding of the specific SBDP120 antibody provide strong evidence for conservation of functional homology.
Our modification of B. burgdorferi to overproduce DbpA and DbpB led to a dramatically increased binding of the specific antibodies to intact spirochetes as showed by immunofluorescence, indicating that both adhesins are surface exposed.
Cell ELISA could demonstrate binding of the specific scFvs to the cell surface expressed PLAP.
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The binding enthalpies of the specific and non-specific DNA binding to the protein differed significantly.
These matrices enable people to assign a quantitative score to any sequence to evaluate the binding affinity of the specific TF at that sequence.
Lastly, in liver STAT5 binding significantly coincides with binding of the cell-specific transcription factors HNF4A, FOXA1 and FOXA2 and is associated with cell-type specific gene transcription.
Thus this technique can potentially be used to study the dose-dependent saturating binding of the ADAMTS13-specific monoclonal antibodies.
However, maximal binding of the α2-specific ligand was much higher in KCs from CLP animals (Fig. 2A).
More suggestions(13)
binding of the immunoconjugate
binding of the polyclonal
binding of the secondary
binding of the hybrid
binding of the former
binding of the different
binding of the non
binding of the same
binding of the individual
binding of the targeted
determining of the specific
binding of the existing
binding of the selected
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