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At the same time the sequence diversity at the common footprints allows for binding of different glycans or differential binding of the same glycan.
These results were confirmed by detecting a specific binding of the same mAbs to CHO cell transfected with a TfRC expression plasmid (data not shown).
Therefore, with the binding of the same amount of antibody to the protein complex-GNP conjugates, the particle size should be just slightly smaller in the case of anti-Src assay solution than anti-Stat3 assay solution.
Based on size similarities of 30 45 kD, the UV-crosslinking assay suggested binding of the same proteins to the 3'terminal parts of the EfnA1, EphA2, and EphA4 3'UTRs (Fig. 3b).
In agreement with this reduced amino acid similarity in intracellular sequences, a recent study showed that the binding of the same agonist to either CB1 or CB2 receptors leads to differential activation of G-proteins [33].
In some instances slightly different motifs for binding of the same transcription factor have been reported.
Similar(41)
The conserved domain of Dictyostelium Myb is capable of binding to the same DNA sequence as the vertebrate and Drosophila Myb proteins.
However, immunohistochemistry has demonstrated that RUNX1 and RUNX1/ETO are targeted to different subnuclear compartments (McNeil et al., 1999), a scenario that would be difficult to reconcile with a rapid exchange of factors binding to the same region of chromatin.
Different from those established methods, our approach goes beyond multiple bindings of the same ligand to a homogeneous oligomer (as in the binding of oxygen to haemoglobin [ 9]): We consider here the construction of heterogeneous protein assemblies mediated by multiple binding surfaces on adaptor proteins.
A series of molecules binding to the same protein active site is drawn in a graphically consistent way.
Motilin is another gastro-intestinal peptide hormone related with ghrelin structurally, binding to the same family of G protein-coupled receptors.
More suggestions(15)
binding of the anti-AT1R
binding of the active
binding of the fourth
binding of the targeted
binding of the immunoconjugate
binding of the polyclonal
binding of the secondary
binding of the former
binding of the hybrid
binding of the different
binding of the non
binding of the mutant
binding of the agonist
binding of the individual
binding of the primary
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