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CadC variants with distinct amino acid replacements, which cause a stimulus-independent ON-phenotype, corroborated our conclusion that clusters of CadC indicate binding of the receptor to the DNA.
Crystal structures show that antibodies in this class engage the hemagglutinin RBS and mimic binding of the receptor, sialic acid, by supplying a critical dipeptide on their projecting, heavy-chain third complementarity determining region.
Our and other's results showed that the extracellular loop between S3 and S4 segments on DIV of sodium channels are critical for the binding of the receptor site 3 scorpion toxins (Bosmans and Tytgat, 2007).
For example, applying different in vivo strategies, a model was proposed for repression by GR which involves tethering, or direct binding of the receptor to an other transcription factor [19], notably AP1 [20] and NF-κB [21].
Indiscriminate binding of the receptor to sequences independently of their degree of similarity to the DUES, however, would loosen or even abolish the drive responsible for the emergence and gradual accumulation of DUESs in the genome.
These different modes include direct binding of the receptor to estrogen response elements (EREs).
Similar(37)
The binding of the receptors and their ligands has the characteristics of specificity, selectivity, strong affinity, and obvious biological effect.
Indeed, these aminoacid changes (D283H and K207N) may affect the binding of the receptors to their ligands and therefore possibly disrupt the normal signalling cascade.
Their genomic mediated pathway include steps as binding of ligand to receptor, translocation into nucleus and binding of the receptor-ligand complex to a specific DNA response element causing a gene response.
These receptors have a C-terminal and an N-terminal zinc-finger domains that mediate binding of the receptors to target DNA sequences.
The two most common are binding to the ligand-binding site of the receptor and, conversely, binding to the receptor-binding site of the ligand.
More suggestions(17)
binding of the cofactor
binding of the antibody
binding of the viral
binding of the sera
binding of the outbreak
binding of the myosin
binding of the peptide
binding of the fusion
binding of the radiolabel
binding of the radioligand
binding of the heterodimer
binding of the target
binding of the ligand
binding of the karma
binding of the initiator
binding of the nation
binding of the protein
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