Sentence examples for binding of the negatively from inspiring English sources
Positively charged amino acids are involved in coordinating the binding of the negatively charged phosphates of ATP.
On the other hand, there are adjacent positively charged patches on the HEN1 surface, which may be involved in the binding of the negatively charged RNA backbone, but they correspond to variable region around motifs III and X.
Based on these studies, a model of how ATP binds to the receptor was proposed, with lysine residues 68, 70 and 309 coordinating the binding of the negatively charged phosphate tail of ATP.
In addition, no significant alterations in the binding of the negatively acting modifications, tri-methyl lysine 9 of histone H3 and tri-methyl lysine 20 of histone H4, at the telomerase gene promoters were associated with either hTR or hTERT expression.
In HR, this unprotonated carboxylate is replaced by Thr (Supporting Information Figure 1), suggesting that the electric quadrupole of the RSBH+ with its counterion complex (Asp85, Asp212, and Arg82 in BR) lacks a negative charge and the charge balance is compensated for by the binding of the negatively charged chloride ion.
Aryl sulfatases, for example the enzyme PAS from P. aeruginosa, relies on Ca2+ for proper orientation and binding of the negatively charged substrate (Boltes et al. 2001), whereas the alkyl sulfatase Pisa 1 from Pseudomonas sp. DSM 6611 needs two Zn2+ ions for water activation to provide a good nucleophile [OH−] for the hydrolytic cleavage.
We propose that polymers with high positive charge density are capable of binding to the negatively charged endosomal membrane.
This binding of oxidized GAPDH to the outer membrane of the damaged mitochondria may be mediated by oxidation-dependent exposure of positively charged patch in GAPDH, which enables its binding to the negatively charged head groups of phospholipids (Morero et al, 1985; Glaser & Gross, 1995).
In this work we demonstrated the phenomenon of competition of some earlier designed polycationic peptides and fluorescent probes for their binding to the negatively charged inner membrane of mitochondria and to the PC/PG (9 1) liposomes.
This allows the mineral to withstand the binding activity of the negatively charged mucin layer and results in lower competition between minerals of similar charge in their resorption from the gut and transfer to the enterocyte.
