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The binding of the molecules is mediated by free radicals, present on the surface of the plasma-treated PET.
The autodock program was used to study the binding of the molecules to HIV-1 the reverse transcriptase enzyme.
The results indicate that the binding of the molecules to the therapeutic target is not essential to produce a lethal effect on cancer cells of the brain and that antiangiogenic efficiency is much more important.
Despite this repulsion, electron transfer from graphene into the molecules results in very strong binding of the molecules to the graphene (more than 1.8 eV per molecule, as shown in Figure 3 c).
The neutral case is identical to what is shown in Figure 3 c and results in overall binding of the molecules to graphene (negative energy) but an increasing energy with increased molecular density.
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Biological investigation also confirmed the irreversible binding of the molecule with the FGFR1-3 target kinases.
The interaction of isoprene with molybdenum disulphide has been studied by computer-assisted modelling of the binding of the molecule at active sites.
Bispecific binding of the molecule to ErbB2 on the surface of tumor cells and to the B7 counter receptor CTLA-4 was demonstrated by FACS analysis.
The simulations demonstrate that even at room temperature the binding of the molecule to the acid site is frequently broken such that only the vdW interaction between the alkane and the zeolite remains.
The different side groups affect the binding of the molecule to the GABAA receptor and so modulate the pharmacological properties.
The binding of the molecule to the PTH receptor-1 activates adenylate cyclase and several phospholipases (A, C, D) and increases intracellular cAMP and calcium levels.
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