Sentence examples for binding of the membrane from inspiring English sources
Accumulation of sterols in the ER membrane triggers binding of the membrane domain of HMGCoAR to a subset of Insigs, which carry a membrane-anchored ubiquitin ligase called GP78 which ubiquitinates HMGCoAR, marking it for proteasomal degradation [83].
Total cellular expression of mAChRs was measured using the binding of the membrane permeable radioligand [3H]quinuclidinyl benzilate ([3H]QNB) to intact cells using a previously described method [34].
Cell surface expression of mAChRs was measured using the binding of the membrane impermeable radioligand N-[3H]methylscopolamine ([3H]NMS) to intact cells using a previously described method [33].
On the other hand, higher levels of sCTLA-4 could contend the binding of the membrane form of CTLA-4 with CD80/CD86, in later activation phase, causing a reduction of inhibitory signalling.
On the plasma membrane, this configuration of the plexin dimer orients the active sites of the two GAP domains toward the membrane surface and leaves sufficient space for binding of the membrane anchored Rap substrate, as observed in the PlexinC1cyto/Rap1B complex structure.
Here, the y-axis is the initial rate of HA binding on the membrane surface.
Nonspecific binding of the membranes was blocked with Tris-buffered saline (TBS) containing 1% (w/v) nonfat dry milk and 0.1% (v/v) Tween-20 (TBST) for more than 2 h.
Immunoprecipitation experiments indicate that the β3 intrasubunit C2 24 disulfide bond is required for homophilic binding of the membrane-localized β3 subunit in vivo.
Non-specific binding of the membranes was blocked with Tris-buffered saline (TBS) containing 1% (w/v) nonfat dry milk and 0.1% (v/v) Tween-20 (TBST) for more than 2 h.
In the case of Ci-VSP, the structural similarity to PTEN would suggest a similar orientation of binding to the membrane.
