The phrase "binding of the ligand" is correct and usable in written English.
You can use it when you are referring to the process of two molecules bonding together. For example: "The binding of the ligand to the receptor was essential for the proper functioning of the organ."
It is well established that sFas may bind to membrane-bound FasL, thus blocking binding of the ligand to the Fas receptor and preventing apoptosis induction in the target cell.
Soluble Fas (sFas) can bind to membrane-bound FasL, thus blocking the binding of the ligand to the Fas receptor, preventing apoptosis induction in the target cell, and enhancing the immunosuppressive effects of tumors.
JAKs bind to some cell surface cytokine receptors, and the binding of the ligand to the receptor triggers the activation of JAKs, which phosphorylate tyrosine residues on the receptor.
Do these really pinpoint the actual functional groups involved in the non-covalent binding of the ligand to the active site?
Although the global motion of SH2 domain regulates Csk function, little is known about the relationship between the disulfide bond and binding of the ligand.
The relationship between ligand and transportate properties indicated that the initial binding of the ligand to hPEPT1 is the major determinant for translocation of the investigated dipeptides.
Physiologically, GABA receptors are activated upon binding of the ligand, GABA.
As shown in Figure 1, binding of the ligand, the hormone erythroprotein (Epo) to the receptor activates the receptor associated Janus kinase (JAK) by phosphorylation, which in turn results in the recruitment of monomeric Stat5.
In normal physiological conditions, Met is expressed primarily by epithelial cells at the cell surface and is activated through paracrine binding of the ligand hepatocyte growth factor/scatter factor (HGF/SF) [5], [6], [7].
Previous attempts to model the ligand interactions of the CCR5 ligand identified the same cavity within the chemokine structure but showed the binding of the ligand to be primarily dependent on interaction with the TM1, TM2, TM3 and TM7 helices.
Finally we show that the 'phantom ligand effect' of the LG100754 is due to a direct binding of the ligand to RAR that stabilizes coactivator interactions thus accounting for the observed transcriptional activation of RAR/RXR.
