Sentence examples for binding of the lectin from inspiring English sources

Benzyl-α-GalNAc also inhibited maturation of  O-linked glycans  in Colo205 cells, demonstrated by the observed increase in binding of the lectin peanut agglutinin (PNA), which binds to the T-antigen disaccharide.

In order to determine whether the CSPG-related patches represent specific binding of the lectin, we treated one hemisphere of P4 mice with ChABC.

Simultaneously, in clinical studies of malignant melanoma, binding of the lectin HPA indicating aberrant glycosylation, and upregulation of the cell adhesion molecules CEACAM1 and L1, have been correlated with metastatic spread (Thies et al, 2001, 2002a, 2002b).

Ultrastructural and molecular characterisation shows that these cells have an abundance of large apical secretory vesicles, which contain highly glycosylated material, positive for binding of the lectin, peanut agglutinin, and an antibody to the carbohydrate epitope, HNK-1.

Over-expression of N-acetylgalactosamine glycoproteins as detected by binding of the lectin from Helix pomatia (HPA), is associated with metastatic competence and poor patient prognosis in a range of human adenocarcinomas.

Constructs were transfected into CHO cells and stable populations selected for hygromycin resistance were examined for resistance to the toxicity of Phaseolus vulgaris leukoagglutinin (L-PHA), and/or binding of the lectin Galanthus nivalis agglutinin (GNA).

In laboratory studies, erythrocytes expressing blood group A1, the primordial human ABO type (Calafell et al, 2008), exhibit strong rosette formation through binding of the lectin-like domain of PfEMP-1 (Carlson & Wahlgren, 1992; Vigan-Womas et al, 2012), while the evolutionarily more recent group O erythrocytes rosette least (Rowe et al, 2007).

DAB was used as visual indicator to specifically localise the binding of the lectins to the tissues.

We furthermore analysed binding of the lectins PHA-L and WGA, which indicated metastatic spread of murine B16 melanoma cells (Tao et al, 1982), but are not correlated with melanoma metastasis in man (Thies et al, 2001).

According to Wong et al. [ 36], lectins do not directly inhibit fungal growth by changing the structure and/or permeability of the fungal membrane but rather by indirect effects produced by the binding of the lectins to carbohydrates on the surface of the fungal cell wall.

All PBS washes were conducted at room temperature and each wash was done two times for 5 min. The binding of the lectins to the prostate tissues was revealed by a brown colour, as a result of the DAB reaction with the streptavidin-conjugated peroxidase solution.